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Implementation Toolkit for Small and Sick Newborn Care: bridging the know-do gap through co-design of a global open-access knowledge management web platform and linked community

Allison, L. E.; Sipalo, M.; Whatley, T.; Griffiths, Z.; Gathara, D.; Murless-Collins, S.; Ezeaka, C.; Bolaji, O.; Chiume, M.; Salim, N.; Walker, K.; Stevenson, A.; Hale, R.; Ndiaye, O.; Magge, H.; Salvadori, M.; Cassera, F.; Khadka, N.; Degefie Hailegebriel, T.; Richards-Kortum, R.; Oden, M.; Lincetto, O.; Liaghati-Mobarhan, S.; Ruysen, H.; Cocoman, O.; Gibson, A.; Gupta, G.; Lawn, J. E.

2026-03-03 health systems and quality improvement
10.64898/2026.03.02.26347429 medRxiv
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BackgroundMost births worldwide (>80%) occur in health care facilities, yet 2.3 million newborns die annually. If the know-do gap between evidence and implementation was closed, an estimated 752,000 newborn deaths could be prevented per year. To bridge this gap, we describe the co-design of the Implementation Toolkit for Small and Sick Newborn Care (Newborn Toolkit), a web platform and linked community of global implementers, facilitated by NEST360 and UNICEF. The Newborn Toolkit enables access to practical, curated resources, including tools for peer learning and adaptation to country contexts. MethodsA systematic three step process was followed. Step 1) Structure: We used an organising framework of WHO and UNICEF ten core components for health systems strengthening. We then reviewed relevant knowledge management platforms to identify elements facilitating user engagement. Step 2) Content: >300 implementers collated publications and tools for ten core components. Step 3) Refining and building community: User data analytics and surveys plus direct feedback from the global communities of practice provided data to improve website and webinar content. ResultsStep 1) Structure: In 2020, the Newborn Toolkit website structure was co-designed based on the ten core components. Step 2) Content: Working groups, organised by core components, collated over 1,100 resources in 15 languages. Step 3) Refining and building community: Cross-country learning was facilitated through 45 webinars with multi-disciplinary speakers from all continents including caregivers, clinicians, non-governmental organisation representatives, engineers, and data scientists. French language translation and engagement was added between 2023-2025. Unique user counts increased with 28,146 in 2023 to 62,561 in 2025 from 198 countries and territories. The most viewed content includes WHO guidelines, neonatal floor plans, the ABC device costing tool, and data tools. ConclusionsGiven the urgency for accelerated progress for newborn survival by 2030, rapid implementation of proven solutions is needed. It is crucial that implementers can access evidence and tools to adapt for their specific context, rather than "reinventing the wheel". Systems change is complex, requiring novel approaches to make it doable, such as standard, simplified action pathways available on the Newborn Toolkit. Gaps to address include evidence availability in multiple languages. KEY FINDINGSO_LIWHAT WAS KNOWN? O_LI2.3 million neonatal deaths are estimated annually and 65 countries are at-risk of missing Sustainable Development Goal 3.2 of reducing the number of neonatal deaths to less than 12 per 1,000 live births by 2030 C_LIO_LIThere exists a know-do gap in global newborn health referring to the inability to translate evidence, what is known to work, into practice to improve health outcomes for WHO-UNICEF level-2 Small and Sick Newborn Care C_LIO_LIFrameworks based on country experiences have been created to guide health systems strengthening such as the WHO/UNICEF core components; however, operationalisation is needed C_LIO_LIEvidence, guidelines, and resources for Small and Sick Newborn Care were available; however, there existed a gap in knowledge management platforms dedicated to enabling evidence-based implementation of health systems strengthening interventions in low-resource settings C_LI C_LIO_LIWHAT WAS DONE THAT IS NEW? O_LIWe co-designed a knowledge management platform for resources including tools, readings, and case studies to bridge the know-do gap for Small and Sick Newborn Care in low-resource settings C_LIO_LIContent and resources on the site were organised according to the ten WHO/UNICEF core components for health systems strengthening plus infection prevention and control C_LIO_LIThis platform was operationalised and scaled by linking to, and engaging with, a global community of practice C_LIO_LIWe applied a continuous learning and feedback integration approach to develop and refine content, enable accessibility including by language, and tailor engagement initiatives to implementer needs informed by website user and webinar data analytics C_LI C_LIO_LIWHAT WAS FOUND? O_LIThe platform hosts over 1,100 tools and readings with resources available in 15 languages C_LIO_LIBetween 2021-2025, this platform had 157,452 unique users, from 198 countries and territories C_LIO_LI45 webinars were hosted between 2022-2025 showcasing implementation case studies and facilitating cross-country learning C_LIO_LIKnowledge management and targeted engagement can enable uptake of information by organising content in practical, digestible, and feasible formats C_LI C_LIO_LIWHAT NEXT? O_LIThe know-do gap in Small and Sick Newborn Care needs to be closed. Providing up-to-date, relevant evidence that adapts to emerging knowledge and local learning, alongside leadership and financial inputs, could facilitate quality care delivery through data-driven decision making C_LIO_LIBridging language barriers, through content translation, is a priority and crucial to enable wider access to up-to-date evidence C_LI C_LI

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