Expanding the clinical spectrum of autoimmune inflammatory myopathies with prominent B cell aggregates: a case series

2026-03-03 rheumatology Title + abstract only

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Autoimmune inflammatory myopathies (AIM) with prominent B cell aggregates (BCM) on muscle biopsy is an uncommon finding. We aimed to compare the characteristics and clinical course of patients with BCM on muscle biopsy to those without and characterize B cell infiltrates in the muscle of these patients. We performed a retrospective study of subjects with AIM in the Canada Inflammatory Myopathy Study (CIMS) cohort to identify cases with BCM on muscle biopsy, which was defined as [≥]30 CD20+ c...