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Apathy in Mild Behavioural Impairment: Associations with Cortical Thickness and Grey Matter Volume
2026-02-27
psychiatry and clinical psychology
Title + abstract only
View on medRxiv
Show abstract
Mild Behavioural Impairment (MBI) is defined by later-life onset of persistent behavioural changes and is recognized as a risk marker for cognitive decline and dementia. Apathy, a core MBI domain characterized by diminished interest, initiative, and emotional reactivity, can emerge before dementia and is hypothesized to be associated with structural brain changes. While previous studies have explored Alzheimer disease (AD)-related neuroanatomical substrates of apathy in the dementia clinical st...
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