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Segmentation of metabolically relevant adipose tissue compartments and ectopic fat deposits

Haueise, T.; Machann, J.

2026-02-27 radiology and imaging
10.64898/2026.02.25.26347069 medRxiv
Show abstract

Chemical shift-encoded magnetic resonance imaging using high-resolved 3D Dixon techniques enables the non-invasive and radiation-free assessment of whole-body adipose tissue and ectopic fat distribution. Automatic deep learning-based segmentation of metabolically relevant adipose tissue compartments and ectopic fat deposits in parenchymal tissue is the most important image processing step for the quantification of adipose tissue volumes and ectopic fat percentages from whole-body imaging. This work presents a segmentation model dedicated to the segmentation of 19 metabolically relevant adipose tissue compartments and ectopic fat deposits from whole-body Dixon MRI. The trained segmentation model is available upon request. Related post-processing routines to compute volumes and fat percentages are publicly available: https://github.com/tobihaui/WholeBodyATQuantification.

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