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Heterogeneity, Longitudinal Decline, and Metabolic Risk in MRI-Based Quantification of 20 Individual Hip and Thigh Muscles
2026-02-27
radiology and imaging
Title + abstract only
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Quantifying muscle health at scale has been limited by the difficulty of segmenting individual muscles on MRI. We developed an automated 3D deep-learning framework that segments 20 bilateral hip and thigh muscles from Dixon MRI, enabling muscle level quantification of volume and relative fat fraction (rFF). Applied to 10,840 baseline and 2,766 longitudinal UK Biobank scans, this framework supports population-scale phenotyping across demographic, metabolic and treatment exposures. Segmentation ac...
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