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Early Population-Level Impact of Helicobacter pylori Eradication on Gastric Cancer Deaths in Japan: A Counterfactual Analysis of Short-Term Divergence

2026-02-26 epidemiology Title + abstract only
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BackgroundHelicobacter pylori infection accounts for 98% of gastric cancer (GC) cases in Japan. Since 2013, the nationwide expansion of H. pylori eradication therapy to chronic gastritis patients has created a unique opportunity to evaluate its population-level impact on GC primary prevention. However, short-term reductions in GC deaths are difficult to interpret given the long natural history of gastric carcinogenesis. This study aimed to assess the early impact of population-level eradication ...

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