Back

Long-read nanopore sequencing uncovers population-specific structural variation in the Middle East and North Africa

2026-02-23 genetic and genomic medicine Title + abstract only
View on medRxiv
Show abstract

Structural variants (SVs) are a major source of genomic diversity and disease susceptibility; however, populations from the Middle East and North Africa (MENA) region remain critically underrepresented in global reference databases. We provide the first detailed catalogue of structural variation in 61 individuals from diverse MENA countries, using publicly available ultra-long Oxford Nanopore sequencing. A scalable and dual-reference alignment-based method (GRCh38 and T2T-CHM13) was employed to ...

Predicted journal destinations

1
Nature Communications
483 training papers
Top 0.8% 22.9%
2
The American Journal of Human Genetics
77 training papers
Top 0.9% 12.2%
3
Nature Genetics
72 training papers
Top 0.4% 12.2%
4
Genome Medicine
56 training papers
Top 0.3% 8.0%
5
Genetics in Medicine
57 training papers
Top 3% 5.2%
6
Scientific Reports
701 training papers
Top 65% 4.0%
7
Nature
58 training papers
Top 0.5% 3.3%
8
Human Genetics and Genomics Advances
39 training papers
Top 2% 2.9%
9
Proceedings of the National Academy of Sciences
100 training papers
Top 4% 2.2%
10
Cell Genomics
34 training papers
Top 2% 2.0%
11
PLOS Genetics
39 training papers
Top 2% 2.0%
12
eLife
262 training papers
Top 20% 2.0%
13
Nature Medicine
88 training papers
Top 5% 1.6%
14
iScience
74 training papers
Top 8% 1.2%
15
European Journal of Human Genetics
25 training papers
Top 5% 1.2%
16
Human Molecular Genetics
28 training papers
Top 5% 1.2%
17
Frontiers in Genetics
32 training papers
Top 6% 1.0%
18
Communications Biology
36 training papers
Top 4% 0.7%
19
Brain
69 training papers
Top 10% 0.7%
20
Journal of Clinical Investigation
50 training papers
Top 6% 0.7%
21
Journal of Medical Genetics
22 training papers
Top 4% 0.7%
22
Genes
21 training papers
Top 5% 0.7%
23
Science
46 training papers
Top 7% 0.7%
24
Science Advances
52 training papers
Top 5% 0.7%
25
Alzheimer's & Dementia
84 training papers
Top 9% 0.7%
26
npj Genomic Medicine
18 training papers
Top 5% 0.7%
27
PLOS ONE
1737 training papers
Top 99% 0.5%