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Neonatal and Early Childhood Epigenetic Variation Linked to Social and Behavioral Outcomes in Very Preterm Children

2026-02-20 psychiatry and clinical psychology Title + abstract only
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Very preterm infants (<30 weeks gestation) are at elevated risk for neurodevelopmental and social-behavioral challenges. DNA methylation (DNAm) may provide a biological link between preterm birth and later behavioral outcomes. We examined associations between DNAm profiles at neonatal intensive care unit (NICU) discharge and at age 5 with Social Responsiveness Scale (SRS) scores which measure social communication, social interaction, and repetitive behaviors at age 5, including sex-specific effe...

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