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Life-course comorbidity patterns and integrated prediction of postpartum depression, multimorbidity, and symptom progression
2026-02-18
epidemiology
Title + abstract only
View on medRxiv
Show abstract
Perinatal depression (PD) is common and disabling, yet its longitudinal comorbidity patterns and predictability remain poorly understood. This study leveraged 8,804 women with delivery records in the All of Us cohort, including 438 with clinically diagnosed postpartum depression (PPD), to characterize multimorbidity trajectories and develop integrated prediction models. Comorbidities were grouped into 38 conditions across psychiatric, autoimmune, metabolic, neurological/pain, and reproductive/gy...
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