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Infrequent Cannabis Use and Increased Overdose Risk Among People Who Use Unregulated Drugs: Revealing Frequency-Dependent Effects Through Secondary Analysis

2026-02-14 epidemiology Title + abstract only
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BackgroundCannabis use is highly prevalent among people who use unregulated drugs. While daily cannabis use has been hypothesized to provide protective effects through substitution or tolerance mechanisms, the relationship between cannabis use frequency and overdose risk remains poorly understood, particularly for infrequent users. MethodsWe conducted a secondary analysis of cross-sectional interview data from people who use unregulated drugs in Vancouver, British Columbia, collected during the...

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