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An LLM-assisted framework for accelerated and verifiable clinical hypothesis testing from electronic health records
2026-02-12
health informatics
Title + abstract only
View on medRxiv
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Acquiring insights from electronic health records (EHRs) is slowed by manual analytical workflows that limit scalability and reproducibility. We present LATCH (LLM-Assisted Testing of Clinical Hypotheses), an agentic framework that converts natural language clinical hypotheses into fully auditable analyses on structured EHR data. LATCH integrates LLM-assisted semantic layers with deterministic execution pipelines to automate cohort construction, statistical analysis, and result reporting, while ...
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