Back

UniFacePoint-FM: A Foundation Model for Generalizable 3D Facial Representation Learning and Multi-Attribute Prediction

Li, D.; Fu, C.-H.; Tang, K.

2026-02-09 bioinformatics
10.64898/2026.02.06.703926 bioRxiv
Show abstract

The human face is a rich medium for biometric, behavioral, and clinical information. However, 2D facial images based technologies lack critical geometric details and are susceptible to pose and illumination interference, while 3D facial deep learning frameworks are hindered by complex annotation, preprocessing, and task-specific designs with poor cross-domain generalization. To address these challenges, we propose UniFacePoint-FM, a 3D facial foundation model built on a self-supervised Point-MAE framework, tailored for high-fidelity point cloud representation learning. The model was pretrained on a self-constructed dataset of high-resolution 3D facial scans, followed by supervised fine-tuning and comprehensive evaluation across three independent datasets for diverse downstream tasks. Experimental results demonstrate that UniFacePoint-FM is both pretraining-efficient and highly generalizable: it achieves state-of-the-art performance on gender classification, age regression, and BMI prediction, and matches the accuracy of the ResMLP model (while outperforming other baselines) in facial expression recognition. Notably, by learning high-quality, fine-grained representations directly from raw point clouds, UniFacePoint-FM delivers robust generalization and transferability across tasks, datasets, and even different face scanning platforms. Overall, our work establishes an effective foundation model paradigm for 3D facial analysis, with promising implications for biometric security, health monitoring, and advanced human-computer interaction systems.

Matching journals

The top 7 journals account for 50% of the predicted probability mass.

1
IEEE Journal of Biomedical and Health Informatics
34 papers in training set
Top 0.1%
10.6%
2
Nature Communications
4913 papers in training set
Top 17%
10.2%
3
Advanced Science
249 papers in training set
Top 2%
8.5%
4
PLOS ONE
4510 papers in training set
Top 27%
6.5%
5
Scientific Reports
3102 papers in training set
Top 17%
6.5%
6
PLOS Computational Biology
1633 papers in training set
Top 5%
6.4%
7
Science Advances
1098 papers in training set
Top 2%
4.9%
50% of probability mass above
8
Proceedings of the National Academy of Sciences
2130 papers in training set
Top 17%
4.0%
9
Communications Biology
886 papers in training set
Top 2%
3.6%
10
Scientific Data
174 papers in training set
Top 0.6%
3.1%
11
IEEE Access
31 papers in training set
Top 0.2%
2.1%
12
Nature Machine Intelligence
61 papers in training set
Top 2%
1.9%
13
npj Digital Medicine
97 papers in training set
Top 2%
1.9%
14
Briefings in Bioinformatics
326 papers in training set
Top 4%
1.7%
15
IEEE Transactions on Medical Imaging
18 papers in training set
Top 0.3%
1.5%
16
eLife
5422 papers in training set
Top 49%
1.2%
17
iScience
1063 papers in training set
Top 21%
1.2%
18
Bioengineering
24 papers in training set
Top 1.0%
0.9%
19
Nature Methods
336 papers in training set
Top 6%
0.8%
20
Bioinformatics Advances
184 papers in training set
Top 4%
0.8%
21
Computational and Structural Biotechnology Journal
216 papers in training set
Top 9%
0.8%
22
Journal of Pathology Informatics
13 papers in training set
Top 0.4%
0.8%
23
NeuroImage
813 papers in training set
Top 6%
0.8%
24
Patterns
70 papers in training set
Top 2%
0.8%
25
Frontiers in Genetics
197 papers in training set
Top 10%
0.7%
26
European Journal of Human Genetics
49 papers in training set
Top 1%
0.7%
27
Medical Image Analysis
33 papers in training set
Top 1%
0.7%
28
IEEE Transactions on Computational Biology and Bioinformatics
17 papers in training set
Top 0.8%
0.7%
29
Bioinformatics
1061 papers in training set
Top 10%
0.7%
30
Frontiers in Plant Science
240 papers in training set
Top 6%
0.5%