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Clonal Hematopoiesis in HIV and Atherosclerosis, Arterial Inflammation, and Hematopoietic Activity

2026-02-09 cardiovascular medicine Title + abstract only
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BackgroundClonal hematopoiesis of indeterminate potential (CHIP) is associated with cardiovascular disease (CVD) in the general population and is more common among people with HIV (PWH). The mechanisms by which CHIP contributes to atherosclerosis in PWH are unknown. We hypothesized that CHIP is associated with carotid atherosclerosis, arterial inflammation, and hematopoietic activity among PWH. MethodsIn a cohort study, we studied PWH ages 31-74 years. CHIP mutations were detected with a valida...

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