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Genomic atlas of 7,000 plasma proteins and their associations with diseases and traits in East Asian populations
2026-02-06
epidemiology
Title + abstract only
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Proteogenomic studies integrating genetic, molecular, and phenotypic data have transformed target discovery, yet remain heavily biased toward European populations. Here, we present a large-scale proteogenomic atlas in a non-European population, analysing 7,289 plasma proteins profiled by SomaScan v4.1 in 3,965 Chinese adults. Genome-wide association analyses identified 3,212 protein quantitative trait loci (pQTLs), including 1,092 proteins with a cis-pQTL. Integrating these data with East Asian ...
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