Back
#1
23.3%
Top 2%
18.6%
Top 0.8%
12.4%
Top 47%
5.9%
Top 2%
5.3%
Top 0.4%
4.1%
Top 2%
3.2%
Top 1%
2.9%
Top 5%
2.0%
Top 5%
2.0%
Top 2%
1.6%
Top 27%
1.6%
Top 4%
1.4%
Top 5%
1.2%
Top 2%
1.0%
Top 12%
0.8%
Top 4%
0.8%
Top 6%
0.8%
Top 5%
0.8%
Top 10%
0.8%
Trans-eQTLs reveal the architecture of human gene regulatory networks
2026-02-05
genetic and genomic medicine
Title + abstract only
View on medRxiv
Show abstract
Many non-coding variants influence complex traits and diseases through gene regulation, yet the mechanisms linking these variants to downstream biology remain poorly understood. Here, we present eQTLGen Phase 2, a comprehensive genome-wide analysis of gene expression quantitative trait loci (eQTLs) in 43,301 blood samples from 52 datasets. Beyond local cis-effects, this sample size enabled the first systematic mapping of trans-eQTLs at scale. We identify cis-eQTLs for nearly all expressed genes ...
Predicted journal destinations
1
Nature Genetics
72 training papers
2
Nature Communications
483 training papers
3
The American Journal of Human Genetics
77 training papers
4
Scientific Reports
701 training papers
5
Genome Medicine
56 training papers
6
Cell Genomics
34 training papers
7
Human Genetics and Genomics Advances
39 training papers
8
PLOS Genetics
39 training papers
9
Genetics in Medicine
57 training papers
10
Proceedings of the National Academy of Sciences
100 training papers
11
Nature
58 training papers
12
eLife
262 training papers
13
Human Molecular Genetics
28 training papers
14
Frontiers in Genetics
32 training papers
15
Bioinformatics
24 training papers
16
iScience
74 training papers
17
Communications Biology
36 training papers
18
European Journal of Human Genetics
25 training papers
19
npj Genomic Medicine
18 training papers
20
Translational Psychiatry
94 training papers