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Repurposing cardiovascular disease prediction models for cancer
2026-02-04
public and global health
Title + abstract only
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Background: Population cancer screening detects the presence of early-stage disease rather than assessing future disease risk. We evaluated whether widely implemented cardiovascular disease (CVD) risk models can predict 10-year cancer risk, comparing them with the QCancer risk model. Methods: We evaluated four CVD prediction models: QRISK3, PCE, and SCORE2/SCORE2-OP. Models were recalibrated using 20% of the UK Biobank (UKB) cohort and tested in the remainder and in the Clinical Practice Researc...
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