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No evidence for a classic transmission-duration tradeoff in human malaria infections
2026-02-09
infectious diseases
Title + abstract only
View on medRxiv
Show abstract
Pathogenic organisms are typically thought to be constrained by a tradeoff between the rate and duration of transmission, an assumption that underpins a considerable body of evolutionary theory. Here we test for a transmission-duration tradeoff using detailed historical malaria infection data from an era prior to widespread use of antibiotics when humans were deliberately infected with malaria parasites as treatment for neurosyphilis (malariatherapy). These time series follow individual human in...
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