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Linking Cognitive Variability and Alzheimers Disease Biomarkers by Neurocognitive Status

2026-02-02 neurology Title + abstract only
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ObjectiveTo assess intra-individual cognitive variability (IICV) in relation to Alzheimers Disease (AD) biomarkers. MethodsThe sample included 879 adults from the National Alzheimers Coordinating Center, aged 50 and above with a complete neuropsychological evaluation and AD biomarker data available (64% cognitively intact; 36% cognitively impaired). We conducted a series of moderated regression models where AD biomarkers, neurocognitive status, and their interaction effects predicted IICV. IICV...

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