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Ultra-fast sample-to-sequencing workflow for clinical diagnostics using micropillars
2026-01-30
genetic and genomic medicine
Title + abstract only
View on medRxiv
Show abstract
We present a streamlined, solid-phase workflow for Oxford Nanopore sequencing that integrates DNA extraction, purification, and library preparation within a single microfluidic cartridge. By eliminating tube transfers and performing all enzymatic steps directly on captured DNA, the method minimizes sample loss, reduces hands-on time, and simplifies library generation for long-read sequencing. Starting from volumes as small as a single drop of blood, this integrated approach produces high-quality...
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