Redefining Vasoplegia: A New Hemodynamic Model for Differentiating Cardiac vs. Vascular Dysfunction using the Resistance Flow Ratio

2026-01-30 cardiovascular medicine Title + abstract only

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BackgroundConventional definitions of vasoplegia and cardiogenic shock rely on fixed thresholds for mean arterial pressure (MAP), cardiac index (CI), and systemic vascular resistance (SVR), failing to account for the physiologic interdependence between cardiac output and vascular tone. We propose the Resistance:Flow Ratio (RFR = SVRI/CI) as a continuous, physiologically anchored measure to differentiate vascular versus cardiac dysfunction and to unify compensated, decompensated, and mixed shock ...

Redefining Vasoplegia: A New Hemodynamic Model for Differentiating Cardiac vs. Vascular Dysfunction using the Resistance Flow Ratio

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