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Understanding Bladder Cancer Screening Limits Through Comparative Modeling: The Maximum Clinical Incidence Reduction (MCLIR) Methodology
2026-01-30
oncology
Title + abstract only
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BackgroundBladder cancer imposes substantial clinical and economic burden, yet key natural-history quantities that determine the potential effectiveness of screening--such as the size of the screen-detectable preclinical reservoir and the preclinical sojourn time--are largely unobservable. The Cancer Intervention and Surveillance Modeling Network (CISNET) uses standardized stress tests to compare independently developed microsimulation models and to clarify how differences in model structure tra...
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