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Local Adaptation to the Sex Environment: Reciprocal Sex-Limited Selection in Different Thermal Regimes

Melo-Gavin, C.; Liu, M. J.; Agrawal, A. F.

2026-01-25 evolutionary biology
10.64898/2026.01.23.701411 bioRxiv
Show abstract

The shared genome prevents each sex from independently responding to the selection experienced by that sex. We used experimental evolution in Drosophila melanogaster with separate pools of Chromosome 3s for males (male-limited chromosomes) and females (female-limited chromosomes) for 15 generations. Viewing each sex as a separate environment, we performed a reciprocal transplant between the sexes to quantify the strength of local adaptation to each sex environment. Each chromosome type was more beneficial in the sex it had been selected for (i.e., local adaptation to sex). Because it has been postulated that sex differences in selection may depend on how well adapted a population is to the abiotic environment, we performed experimental evolution at two thermal regimes: one benign temperature to which the populations were well-adapted and one novel temperature. Female-specific adaptation was stronger at the benign temperature whereas male-specific adaptation was stronger in the novel temperature. Within chromosome pools, male and female fitness were more positively correlated in the novel compared to the benign temperature. Though males carrying male-limited chromosomes were typically more fit than males carrying female-limited chromosomes, they were also more harmful to their female mating partners.

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