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Subcortex visualization: A toolbox for custom data visualization in the subcortex and cerebellum

Bryant, A. G.

2026-01-26 neuroscience
10.64898/2026.01.23.699785 bioRxiv
Show abstract

Recent years have seen an expanding repertoire of code-based tools for visualizing neuroimaging data, promoting reproducibility and interpretability of brain-mapping findings. However, most open-source visualization packages for the human brain are geared toward the cerebral cortex, and the comparatively few options for the subcortex and cerebellum are limited in scope (i.e., atlas support) and flexibility. We address this critical gap by introducing subcortex_visualization, an open-source package offered in both Python and R, that provides a unified and accessible framework for programmatically visualizing non-cortical data across many popular subcortical and cerebellar parcellation atlases. These visuals are inspired by the ggseg R package for cortical data, which implements standardized rendering conventions to facilitate comparison across atlases in a vectorized two-dimensional format. In addition to the vectorized versions of nine subcortical and cerebellar atlases--to our knowledge, the most comprehensive collection of non-cortical atlases in a single visualization toolbox--we also provide a step-by-step tutorial for users to generate custom vector-based visualizations from any given brain segmentation, enabling flexible extension to new atlases and structures. Collectively, subcortex_visualization and the accompanying documentation support reproducible and interpretable visualization of neuroimaging data below the cortical mantle.

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