PDLP5 regulates aquaporin-mediated hydrogen peroxide transport in Arabidopsis
Li, Z.; Liu, S.-L.; Islam, S.; Clements, M.; Chen, Y.; Aung, K.
Show abstract
Aquaporins facilitate the diffusion of water and small neutral molecules, including hydrogen peroxide (H2O2). In Arabidopsis, plasma membrane intrinsic proteins (PIPs, members of aquaporins) mediate H2O2 transport; however, the regulatory mechanisms governing their activity are not fully understood. Here, we show that plasmodesmata-located protein 5 (PDLP5), a key regulator of plasmodesmal function, negatively regulates PIP-dependent H2O2 transport. PDLP5 forms complexes with PIPs, with its extracellular domain predicted to associate with the extracellular face of the channel. PDLP5 overexpression suppresses H2O2 uptake and confers reduced sensitivity to H2O2-induced root growth inhibition, whereas pdlp5 mutants display the opposite phenotype. We further identify PIP2;5 as a critical component of PDLP5-mediated regulation. These findings reveal an extracellular mechanism for modulating aquaporin function, expanding current models of channel regulation in plants.
Matching journals
The top 2 journals account for 50% of the predicted probability mass.
Similar papers in this journal
Similar papers in this journal
- Humidity-driven ABA depletion determines plant-pathogen competition for leaf water 97%
- Genetic architecture of a light-temperature coincidence detector 97%
- Transporter-mediated depletion of extracellular proline directly contributes to plant pattern-triggered immunity against a bacterial pathogen 97%
Similar papers in this journal
- S1 basic leucine zipper transcription factors shape plant architecture by controlling C/N partitioning to apical and lateral organs 97%
- PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana 97%
- An AINTEGUMENTA phospho-switch controls bilateral stem cell activity during secondary growth 96%
Similar papers in this journal
- ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate homeostasis in Arabidopsis 97%
- Cell fate plasticity of xylem-pole-pericycle in Arabidopsis roots 95%
- Primary carbohydrate metabolism genes participate in heat stress memory at the shoot apical meristem of Arabidopsis thaliana 94%
Similar papers in this journal
- Cytoplasmic calcium influx mediated by Lr14a regulates stomatal immunity against leaf rust in wheat 97%
- An Evolutionarily Conserved Receptor-like Kinases Signaling Module Controls Cell Wall Integrity During Tip-Growth 96%
- A peptide pair coordinates regular ovule initiation patterns with seed number and fruit size 96%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.