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Age and the Diurnal Oscillatory Features of the Human Chronobiome
2026-01-23
cardiovascular medicine
Title + abstract only
View on medRxiv
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The molecular clock regulates diverse aspects of human biology. As people age, diurnal rhythms deteriorate, most evidently in the daytime napping and nighttime waking of older individuals. To understand how temporal deconsolidation of oscillatory networks could contribute to age-related disease expression, we studied the chronobiome at unprecedented depth in young and old apparently healthy individuals. Transomic integration segregated age groups and identified candidate mechanisms by which osci...
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