Administration of Normal Saline versus Ringers Lactate in Critically Ill Patients: A Protocol and Statistical Analysis Plan for a Secondary Analysis of the FLUID trial (FLUID-ICU)

2026-01-19 intensive care and critical care medicine Title + abstract only

Show abstract

IntroductionRecent evidence from randomized controlled trials and meta-analyses in the critically ill suggest small but clinically important differences in death and requirement for renal replacement therapy that favor Ringers lactate as compared to normal saline. To futher contribute to this evidence base, we will perform a secondary analysis of the FLUID trial with a focus on critically ill patients (FLUID - ICU). The FLUID trial was hospital wide cluster randomized cross-over trial that compa...

Administration of Normal Saline versus Ringers Lactate in Critically Ill Patients: A Protocol and Statistical Analysis Plan for a Secondary Analysis of the FLUID trial (FLUID-ICU)

Predicted journal destinations