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High initiation but sub-optimal completion of tuberculosis preventive treatment among people living with HIV on ART, persistent tuberculosis incidence and programmatic implications: Findings from a two-year multi-country cohort study
2026-01-21
public and global health
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BackgroundTB preventive treatment (TPT) is recommended for those at risk of TB, but despite encouraging trial data, evidence of its effectiveness from routine settings with diverse TPT regimens is limited. We describe routine TPT implementation outcomes in people living with HIV (PLWH) to identify bottlenecks and opportunities for improvement along the cascade of care. MethodsFrom 2021-2023, we conducted a 24-month prospective cohort study of PLWH in nine health facilities in Ethiopia, South Af...
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