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Psychedelics distinctly alter brain entropy and complexity compared to psychostimulants
2026-01-16
pharmacology and therapeutics
Title + abstract only
View on medRxiv
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Classical psychedelics have regained interest for their potential to treat psychiatric and neurological disorders, and explore neural mechanisms supporting perception, cognition, and mood. Acute psychedelic effects have been linked to increases in brain complexity and entropy, but it is unclear if these changes are specific to psychedelics or reflect more general psychoactive effects. Here, we examined whether brain complexity and entropy metrics can identify features specific to the psychedelic...
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