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Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

2026-01-16 urology Title + abstract only
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BackgroundChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of adaptive immune responses and DNA methylation in CP/CPPS pathogenesis. MethodsVoided bladder 3 (VB3) urine samples from CP/CPPS patients and healthy controls were analyzed for CD4 T cell...

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