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Alveolar Immune Profiling Identifies Distinct Subphenotypes of Acute Respiratory Failure

2026-01-15 respiratory medicine Title + abstract only
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Acute respiratory failure causes millions of deaths worldwide each year, highlighting the need for a better understanding of its pathophysiology and approaches to identify treatment-responsive subphenotypes of patients. Although subphenotypes of acute respiratory failure have been described using peripheral blood biomarkers, it remains unclear whether lung-specific molecular profiles can define biologically and clinically meaningful subphenotypes. In this study, we identified four distinct subph...

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