Vasculopathy as a Mechanical Barrier to Cancer Spread: Clinical Evidence and a Rheology-Based Model in Lung Cancer

2026-01-15 oncology Title + abstract only

Show abstract

Metastatic dissemination in lung cancer (LC) and other solid tumors is influenced not only by tumor-intrinsic biology and immune-inflammatory responses, but also by the physical properties of the vascular system through which circulating tumor cells (CTCs) migrate. Peripheral arterial disease (PAD), particularly when manifesting as aneurysmal dilation, is frequent among long-term smokers and is associated with chronic vascular inflammation and altered hemodynamics. We hypothesized that PAD-relat...

Vasculopathy as a Mechanical Barrier to Cancer Spread: Clinical Evidence and a Rheology-Based Model in Lung Cancer

Predicted journal destinations