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Fine-scale genetic structure and population-specific clinically relevant variants in the indigenous tribal populations of India

2026-01-13 genetic and genomic medicine Title + abstract only
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India harbors one of the most complex demographic and genetic landscapes globally, comprising more than 4600 endogamous ethnolinguistic groups shaped by multiple waves of migration, prolonged isolation and deep social stratification. Odisha, an eastern state of India, is home to 62 indigenous tribal groups, including 13 Particularly Vulnerable Tribal Groups (PVTGs), many of which remain genetically understudied. These populations provide a unique opportunity to explore fine-scale population stru...

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