Protective and Susceptibility Clusters of Environmental Factors, Gene Expression, Antibody Responses, and Cytokines in Pediatric Atopic Dermatitis: Insights from Multi-Modal Data Integration

2026-01-13 allergy and immunology Title + abstract only

Show abstract

BackgroundAtopic dermatitis (AD) is a chronic skin disease that typically occurs in early childhood. In this cross-sectional case-control study, our objective was to employ machine learning approaches to identify novel clusters of protective or susceptibility features associated with AD. Methods and FindingsWe utilised an integrated dataset comprising previously established environmental, cytokine, antibody, and gene expression data from AmaXhosa children, both healthy and with AD, living in ei...

Protective and Susceptibility Clusters of Environmental Factors, Gene Expression, Antibody Responses, and Cytokines in Pediatric Atopic Dermatitis: Insights from Multi-Modal Data Integration

Predicted journal destinations