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A novel functional assay based on patient-derived endometrial organoids and blastoids predicts the success of embryo transfer
2026-01-12
sexual and reproductive health
Title + abstract only
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Successful embryo implantation requires complex interactions between the embryo and the endometrium. Improvements in embryo testing have led to increased success rates for embryo transfer following in vitro fertilization, however, even with euploid embryos under ideal conditions, failure occurs in more than 30% of cases. Methods for diagnosing and improving endometrial function are currently lacking. Here we developed a functional test ("Simbryo FX") for the ability of the endometrium to support...
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