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A Deep Learning Enabled Single Cell Morpholomic Atlas of Nasal Swabs Distinguishes Chronic Inflammation from Sinonasal Malignancy

2026-01-11 otolaryngology Title + abstract only
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BackgroundSinonasal malignancies frequently present with symptoms overlapping chronic inflammatory conditions such as chronic rhinosinusitis (CRS), complicating early detection and delaying treatment. A fast, scalable, non-invasive approach capable of resolving immune and epithelial cell states across inflammatory and malignant disease from routine nasal swabs could substantially improve clinical screening, leading to the initiation of appropriate treatment. MethodsWe developed a deep learning-...

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