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Non-reproducibility of wearable accelerometer methods in protective association between physical activity and cardiovascular disease: a cohort study.

2026-01-08 epidemiology Title + abstract only
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BackgroundThe selection of accelerometer processing methods may influence the shape of the dose-response association between wearable-measured physical activity and health outcomes. We compared the association of stroke and myocardial infarction with Moderate-Vigorous Physical Activity (MVPA) assessed by three accelerometer-generated metrics: modified Euclidean Norm Minus One (ENMO), Machine learning (ML), and activity counts. MethodsWe computed MVPA durations in the UK Biobank accelerometer su...

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