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Rapid loss of doxycycline effectiveness against gonorrhea after implementation of post-exposure prophylaxis in southern California: an observational study
2026-01-08
epidemiology
Title + abstract only
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BackgroundPost-exposure prophylaxis with doxycycline (doxyPEP) within 72 hours after sex is recommended to prevent chlamydia, gonorrhea, and syphilis among United States men who have sex with men (MSM) and transgender women (TGW). However, concerns surround potential expansion of Neisseria gonorrhoeae lineages harboring antimicrobial resistance (AMR) in settings that implement doxyPEP. MethodsWe assessed the effectiveness of doxyPEP against chlamydia, gonorrhea, and syphilis among individuals r...
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