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Causal Modulation of Brain Body Habituation Dynamics Implicates Salience Network Mechanisms in Anxiety

2026-01-06 psychiatry and clinical psychology Title + abstract only
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Anxiety is marked by exaggerated vigilance which may be linked to impaired sensory habituation, yet the physiological mechanisms linking anxiety to dysregulated habituation in the brain remain unclear. The brains ability to filter sensory input is characteristic of healthy functioning and disruption of this can lead to over-responsiveness and hypervigilance that may underlie pathological anxiety. Here, we examined how state and trait anxiety relate to acoustic startle reflex habituation across s...

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