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LncRNA CDKN2B-AS1 C-Allele: A High-Risk Genetic Determinant in Cancer Susceptibility and Progression Impacting Immune Cell Modulation Dynamics with Therapeutic Implications

2026-01-08 oncology Title + abstract only
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Examining LncRNA-driven cancer biology, our study represents the first comprehensive investigation of the LncRNA CDKN2B-AS1 across multiple cancer types, revealing its genetic basis for cancer susceptibility, and associations with thromboembolic risks and immunological dynamics. Stratification across hematological and non-hematological cancers revealed predominant prevalence rates of the CDKN2B-AS1 C-allele, notably higher in solid tumor malignancies, peaking at 86.8% in colorectal carcinoma (CR...

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