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Apparent RSV-COVID interference is not robust to adjustment for shared testing propensity
2025-12-30
epidemiology
Title + abstract only
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BackgroundViral interference, in which infection with one pathogen reduces susceptibility to another, may influence respiratory virus dynamics. Inference from surveillance data is complicated by time-varying testing behavior that can induce correlated detection patterns independent of biological interaction. MethodsWe developed a multi-pathogen renewal model augmented with a ratio penalty that constrains interference estimates to be consistent with observed log-odds ratios of pathogen positivit...
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