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Uromodulin as a protein and genetic biomarker for hypertension: a detailed systematic review & meta-analysis
2026-01-02
cardiovascular medicine
Title + abstract only
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BackgroundHypertension (HTN) is a major global contributor to cardiovascular morbidity and mortality, and improved biomarkers are needed to better characterize individual risk, disease progression, and treatment response. Uromodulin (UMOD), the most abundant protein in human urine reflects tubular health and renal sodium handling. Genome-wide association studies (GWAS) have identified common UMOD promoter polymorphisms associated with HTN across diverse populations, sparking interest in UMOD as ...
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