Unstable sleep and rest-activity rhythms in adolescents at-risk for bipolar disorder: links to mood symptoms and the effect of sleep stabilization

2025-12-30 psychiatry and clinical psychology Title + abstract only

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BackgroundAdolescents with a parental history of bipolar disorder (BD; High-Risk) are more likely to develop BD than those without such history (Low-Risk). Actigraphy studies in adults indicate that instability in sleep and rest-activity rhythms (RAR) may be associated with progression to BD. However, it remains unclear whether High-and Low-Risk adolescents are differentially affected by sleep/RAR instability and their impact on emerging mood symptoms. MethodsWe recruited 50 adolescents unaffec...

Unstable sleep and rest-activity rhythms in adolescents at-risk for bipolar disorder: links to mood symptoms and the effect of sleep stabilization

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