High dimensional tissue specific regulatory codes embedded in viral coding regions
Davidson, A.; Parr, M.; Totzeck, F.; Churkin, A.; Barash, D.; Frishman, D.; Tuller, T.
Show abstract
Viruses co-evolve with their hosts and adapt various genomic level strategies to ensure their fitness. Previous studies have demonstrated that viruses share high dimensional silent patterns with their hosts. In this study, based on a novel computational measure, we demonstrated for the first time that this high dimensional information encodes regulatory codes related to viral tropism.
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