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Unveiling prognostic genes and regulatory mechanisms of exosome in prostate cancer: an integrated analysis of bulk transcriptomics and single-cell RNA sequencing data

2025-12-27 oncology Title + abstract only
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ObjectiveProstate cancer (PCa) constitutes a considerable public health concern worldwide, primarily attributable to its elevated mortality rates. Changes in exosome are shown to significantly influence tumor development. This study aimed to investigate the prognostic value of exosome-related genes (ERGs) in PCa. MethodsPCa single-cell RNA sequencing (scRNA-seq) and transcriptome datasets were obtained from public databases, with ERGs extracted from existing literature. Candidate genes were ide...

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