Back
#1
22.3%
Top 0.3%
22.3%
Top 0.7%
9.0%
Top 0.2%
6.4%
Top 5%
4.2%
Top 28%
3.9%
Top 4%
3.9%
Top 1%
2.8%
Top 80%
1.9%
Top 2%
1.9%
Top 1%
1.9%
Top 6%
1.6%
Top 3%
1.3%
Top 2%
1.3%
Top 7%
1.2%
Top 39%
1.2%
Top 11%
1.0%
Top 4%
1.0%
Top 13%
0.7%
Top 7%
0.5%
Integrated Biofluid Proteomics Identified Dynamic Functional Biomarkers of LRRK2-Linked Parkinson's Disease Progression
2025-12-29
neurology
Title + abstract only
View on medRxiv
Show abstract
Leucine-rich repeat kinase 2 (LRRK2) variants are the most common cause of inherited Parkinsons disease (PD), and the hyperactivity of the LRRK2 variants represent a validated drug target for PD. The penetration of common LRRK2 variants is incomplete, underscoring the need for molecular biomarkers that predict disease onset and guide therapeutics development. Here, we analyzed large datasets of cerebrospinal fluid (CSF) and urinary proteomics from the Parkinsons Progression Markers Initiative (P...
Predicted journal destinations
1
Brain
69 training papers
2
Movement Disorders
49 training papers
3
npj Parkinson's Disease
35 training papers
4
Annals of Neurology
43 training papers
5
Brain Communications
79 training papers
6
Nature Communications
483 training papers
7
Alzheimer's & Dementia
84 training papers
8
Neurobiology of Aging
29 training papers
9
Scientific Reports
701 training papers
10
Journal of Neurology, Neurosurgery & Psychiatry
26 training papers
11
Parkinsonism & Related Disorders
16 training papers
12
Neurology
38 training papers
13
Journal of Neurology
22 training papers
14
Annals of Clinical and Translational Neurology
22 training papers
15
eBioMedicine
82 training papers
16
eLife
262 training papers
17
Frontiers in Neurology
74 training papers
18
Alzheimer's Research & Therapy
31 training papers
19
NeuroImage: Clinical
77 training papers
20
Journal of Alzheimer's Disease
31 training papers