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Acute kidney injury and death in severe falciparum malaria

2025-12-23 infectious diseases Title + abstract only
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BackgroundSerum or plasma concentrations of creatinine and urea are the usual laboratory parameters measured to assess kidney function and disease severity in patients with suspected severe malaria. Creatinine is preferred for estimation of the glomerular filtration rate, but the current threshold for defining severe malaria (> 265 umol/L) is based on adult values and does not reflect the large difference between children and adults in normal values resulting from differences in muscle mass. We ...

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