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High Prevalence of Adolescents At Risk for PCOS and Links to Genetic Susceptibility to PCOS

2025-12-29 endocrinology Title + abstract only
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ImportanceDiagnosis of polycystic ovary syndrome (PCOS) in adolescence is challenging because menstrual irregularity and hyperandrogenism are common in adolescents. Recent international guidelines highlighted an at risk for PCOS category based on either menstrual regularity or hyperandrogenism; however, its population prevalence and genetic correlates remain unknown. ObjectiveTo estimate the prevalence of PCOS and at risk for PCOS in adolescence and evaluate associations with genetic risk for P...

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