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An Integrated Platelet Index Derived From PCA Is Associated With Long-Term Atherothrombotic Risk in Acute Coronary Syndrome
2025-12-17
cardiovascular medicine
Title + abstract only
View on medRxiv
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BackgroundPlatelet morphological indices, such as mean platelet volume and distribution width, reflect platelet turnover and thrombo-inflammatory activity relevant to acute coronary syndrome (ACS), but their individual prognostic value remains inconsistent. This study aimed to derive an Integrated Platelet Index (IPI) using principal component analysis (PCA) to capture a multidimensional platelet morphological phenotype influenced by cardiometabolic and inflammatory stress and to examine its ass...
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