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Plasma protein and tumor tissue gene expression analyses in ovarian cancer reveals differentially co-regulated clusters between benign and malignant conditions
2025-12-16
oncology
Title + abstract only
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Ovarian cancer is the deadliest of gynecological cancers and surgery is often necessary for a final diagnosis. Benign cases could be managed more conservatively, avoiding the risks and complications associated with surgery, if accurate diagnostic biomarkers existed. Underlying differences between circulating protein biomarkers and tumor gene expression also restricts interpretation and prioritization of potential biomarkers for diagnosis and potential drug targets. Here, high-throughput affinity...
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