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A Sham Controlled Randomised Trial evaluating the Safety, Acceptability and Efficacy of Autonomic neuromodulation using Trans-Cutaneous vagal sensory stimulation in uncontrolled Hypertensive patients: Rationale and study design of the SCRATCH-HTN Study
2025-12-15
cardiovascular medicine
Title + abstract only
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BackgroundDespite the broad availability of antihypertensive drugs, approximately 40% of hypertensive patients fail to achieve the recommended blood pressure (BP) levels and may require alternative treatment(s). Currently, renal denervation is the only proven non-pharmacological device-based alternative treatment available but is a costly hospital-based invasive procedure that is unlikely to be widely available. Transcutaneous autonomic neuromodulation (tAN), if safe, acceptable and efficacious,...
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